9-(3,4-dimethoxyphenyl)thioxanthenol

Base Information

• Chemical Name: 9-(3,4-dimethoxyphenyl)thioxanthenol
• CAS No.: 476331-74-5
• Molecular Formula: C₂₁H₁₈O₃S
• Molecular Weight: 350.438
• Mol file: 476331-74-5.mol

Synonyms:9-(3,4-dimethoxyphenyl)thioxanthenol

Chemical Property of 9-(3,4-dimethoxyphenyl)thioxanthenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 9-(3,4-dimethoxyphenyl)thioxanthenol

There total 1 articles about 9-(3,4-dimethoxyphenyl)thioxanthenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

thio-xanthene-9-one (492-22-8) + 4-Bromoveratrole (2859-78-1) → 9-(3,4-dimethoxyphenyl)thioxanthenol (476331-74-5)

Guidance literature:

4-Bromoveratrole; With magnesium; ethylene dibromide; In tetrahydrofuran; for 10h; Heating;

thio-xanthene-9-one; In tetrahydrofuran; for 2h; Further stages.; Heating;

DOI:10.1021/jo026009w

Reference yield:

9-(3,4-dimethoxyphenyl)thioxanthenol (476331-74-5) → 9-chloro-9-(3,4-dimethoxy-phenyl)-9H-thioxanthene

Guidance literature:

With chloro-trimethyl-silane; In dichloromethane; dimethyl sulfoxide; for 12h;

DOI:10.1021/jo026009w

Reference yield:

9-(3,4-dimethoxyphenyl)thioxanthenol (476331-74-5) → 5'-O-[9-(3,4-dimethoxyphenyl)thioxanthyl]thymidine

Guidance literature:

Multi-step reaction with 2 steps

1: trimethyl silyl chloride / CH₂Cl₂; dimethylsulfoxide / 12 h

2: DMAP / pyridine

With dmap; chloro-trimethyl-silane; In pyridine; dichloromethane; dimethyl sulfoxide;

DOI:10.1021/jo026009w

upstream raw materials:

thio-xanthene-9-one

4-Bromoveratrole