3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

Base Information

Chemical Name:3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide
CAS No.:1282523-71-0
Molecular Formula:C₂₂H₂₄N₄OS
Molecular Weight:392.525
Hs Code.:

Synonyms:3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

Chemical Property:

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Technology Process of 3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

There total 4 articles about 3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 2210-25-5
N-Isopropylacrylamide

: 1082834-77-2
4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamine

: 1282523-71-0
3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

Guidance literature:: In water; for 16h; Reflux;
DOI:10.1016/j.bmc.2011.01.039

Reference yield:

: 20099-89-2
4-Cyanophenacyl bromide

: 1282523-71-0
3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 1.5 h / Reflux

2: diisobutylaluminium hydride / hexane; toluene / 0 °C / Reflux

3: water / 16 h / Reflux

With diisobutylaluminium hydride; In ethanol; hexane; water; toluene; 3: aza-Michael addition;
DOI:10.1016/j.bmc.2011.01.039

Reference yield:

: 136-95-8,102337-98-4,84293-42-5
2-amino-benzthiazole

: 1282523-71-0
3-(4-(imidazo[2,1-b]benzothiazol-2-yl)benzylamino)-N-isopropylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 1.5 h / Reflux

2: diisobutylaluminium hydride / hexane; toluene / 0 °C / Reflux

3: water / 16 h / Reflux

With diisobutylaluminium hydride; In ethanol; hexane; water; toluene; 3: aza-Michael addition;
DOI:10.1016/j.bmc.2011.01.039