2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole
CAS No.:1571075-08-5
Molecular Formula:C₃₀H₂₆ClFN₆O
Molecular Weight:541.027
Hs Code.:

Synonyms:2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

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Chemical Property of 2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

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Technology Process of 2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

There total 4 articles about 2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1571074-97-9
3-butyl-1-chloroimidazo[1,5-a]pyridine-7-carboxylic acid

: 1020240-69-0
C₁₈H₁₇FN₄O

: 1571075-08-5
2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

Guidance literature:: With trichlorophosphate; Reflux;
DOI:10.1016/j.saa.2013.12.016

Reference yield:

: 321164-69-6
3-butyl-1-chloroimidazo[1,5-a]pyridine-7-carboxylic acid ethyl ester

: 1571075-08-5
2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol; water / Reflux

2: trichlorophosphate / Reflux

With potassium hydroxide; trichlorophosphate; In ethanol; water;
DOI:10.1016/j.saa.2013.12.016

Reference yield:

: 1020238-95-2
C₂₀H₁₉FN₂O₂

: 1571075-08-5
2-(3-butyl-1-chloroimidazo[1,5-a]pyridin-7-yl)-5-(1-(4-fluorobenzyl)-3-p-tolyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / methanol / Reflux

2: trichlorophosphate / Reflux

With hydrazine; trichlorophosphate; In methanol;
DOI:10.1016/j.saa.2013.12.016