(R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol

Base Information

Chemical Name:(R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol
CAS No.:765278-73-7
Molecular Formula:C20H20 Br2 O2
Molecular Weight:452.186
Hs Code.:29071590
European Community (EC) Number:621-589-6,621-673-2
DSSTox Substance ID:DTXSID30983973
Nikkaji Number:J1.672.227H,J2.481.126C
Wikidata:Q72464715
Mol file:765278-73-7.mol

Synonyms:65355-08-0;765278-73-7;(R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol;(S)-(-)-3,3'-DIBROMO-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BI-2-NAPHTHOL;3,3'-DIBROMO-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BI-2-NAPHTHOL;(R)-(+)-3,3'-DIBROMO-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BI-2-NAPHTHOL;3-bromo-1-(3-bromo-2-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-5,6,7,8-tetrahydronaphthalen-2-ol;(S)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol;MFCD03093977;(R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthalenediol;SCHEMBL3928583;DTXSID30983973;5,5'-Bi(7-bromotetralin-6-ol);BCP10131;AKOS015916409;CS-W009650;SC11859;(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthalenediol, 97%;9(Z),11(E)-OCTADECADIENOICACID;AC-26900;AC-26901;DS-13185;CS-0031466;D5107;FT-0641010;FT-0757427;C76044;D72575;A835081;A915509;7-bromo-5-(7-bromo-6-hydroxy-tetralin-5-yl)tetralin-6-ol;(R)-(+)-3,3Dibromo-5,5,6,6,7,78,8-octahydro-1,1-bi-2-naphtol;3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2naphthol;(aR)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthalene-2,2'-diol;(R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-2,2'-dihydroxy-1,1'-binaphthyl;(R)-(+)-3,3'Dibromo-5,5',6,6',7,7'8,8'-octahydro-1,1'-bi-2-naphthol;(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-2,2'-dihydroxy-1,1'-binaphthyl;3,3'-dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diol;3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro[1,1'-binaphthalene]-2,2'-diol;(R)-(+)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2,2'-naphthalenediol, 97%;3-bromanyl-1-(3-bromanyl-2-oxidanyl-5,6,7,8-tetrahydronaphthalen-1-yl)-5,6,7,8-tetrahydronaphthalen-2-ol

Suppliers and Price of (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(-)-3,3''-Dibromo-5,5'',6,6'',7,7'',8,8''-octahydro-1,1''-bi-2,2''-naphthalenediol
250mg
$ 205.00

TCI Chemical
(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol >97.0%(GC)
1g
$ 203.00

Strem Chemicals
(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol, 99%
1g
$ 452.00

Strem Chemicals
(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol, 99%
250mg
$ 151.00

Sigma-Aldrich
(S)-(?)-3,3′-Dibromo-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-bi-2,2′-naphthalenediol 97%
100mg
$ 69.20

Sigma-Aldrich
(S)-(?)-3,3′-Dibromo-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-bi-2,2′-naphthalenediol 97%
1g
$ 183.00

Crysdot
(S)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol 97%
5g
$ 673.00

Crysdot
(S)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol 97%
1g
$ 218.00

ChemScene
(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol 99.50%
1g
$ 134.00

ChemScene
(S)-(-)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-1,1'-bi-2-naphthol 99.50%
5g
$ 523.00

Total 19 raw suppliers

Chemical Property of (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol

Chemical Property:

Melting Point:145.5-148.5 °C(lit.)
Boiling Point:507.3±50.0 °C(Predicted)
PKA:8.02±0.20(Predicted)
PSA：40.46000
Density:1.628
LogP:6.04740
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:451.98096
Heavy Atom Count:24
Complexity:405

Purity/Quality:

97% ^*data from raw suppliers

(S)-(-)-3,3''-Dibromo-5,5'',6,6'',7,7'',8,8''-octahydro-1,1''-bi-2,2''-naphthalenediol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2=C(C(=C(C=C2C1)Br)O)C3=C4CCCCC4=CC(=C3O)Br
Uses (S)-(-)-3,3''-Dibromo-5,5'',6,6'',7,7'',8,8''-octahydro-1,1''-bi-2,2''-naphthalenediol is a reagent in the preparation of peptoid modified silica gel chiral stationary phases and its application to HPLC enantioseparations.

Technology Process of (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol

There total 4 articles about (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39648-74-3,65355-00-2,65355-14-8
(Ra)-5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diol

: 765278-73-7
(R)-3,3’-dibromo-5,5’,6,6’,7,7’,8,8’-octahydro-[1,1’-binaphthalene]-2,2’-diol

Guidance literature:: With bromine; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/anie.202000675

Reference yield:

: 18531-94-7
(R)-1,1'-Bi-2-naphthol

: 765278-73-7
(R)-3,3’-dibromo-5,5’,6,6’,7,7’,8,8’-octahydro-[1,1’-binaphthalene]-2,2’-diol

Guidance literature:: Multi-step reaction with 2 steps

1: platinum(IV) oxide hydrate; acetic acid; hydrogen / 48 h / 22 °C / 760.05 Torr

2: bromine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere

With platinum(IV) oxide hydrate; hydrogen; bromine; acetic acid; In dichloromethane;
DOI:10.1002/anie.202000675

Reference yield:

: 602-09-5
1,1'-bi-2-naphthol

: 765278-73-7
(R)-3,3’-dibromo-5,5’,6,6’,7,7’,8,8’-octahydro-[1,1’-binaphthalene]-2,2’-diol

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen; palladium on activated charcoal / Inert atmosphere; Schlenk technique

2: bromine / dichloromethane / Inert atmosphere; Schlenk technique

With palladium on activated charcoal; hydrogen; bromine; In dichloromethane;
DOI:10.1021/ja512637k