N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide

Base Information

• Chemical Name: N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide
• CAS No.: 869358-35-0
• Molecular Formula: C₄₈H₄₆I₂N₂O₂
• Molecular Weight: 936.714
• Mol file: 869358-35-0.mol

Synonyms:N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide

Chemical Property of N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide

There total 5 articles about N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

N,N'-dibutyl-N,N'-bis-(4-ethynyl-phenyl)-terephthalamide (869358-32-7) + 2,5-diiodo-p-xylene (1124-08-9) → N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide (869358-35-0)

Guidance literature:

With copper(l) iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 45 - 50 ℃;

DOI:10.1039/b510134d

Reference yield:

N,N'-dibutyl-bis(4-iodophenyl)-terephthalamide (869358-30-5) → N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide (869358-35-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 3.557 g / Et₃N; CuI / Pd(PPh₃)4 / benzene / 55 °C

2: 1.93 g / TBAF / tetrahydrofuran

3: 41 percent / Et₃N; CuI / Pd(PPh₃)4 / tetrahydrofuran / 45 - 50 °C

With copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; benzene; 1: Sonogashira coupling / 3: Sonogashira coupling;

DOI:10.1039/b510134d

Reference yield:

N,N'-dibutyl-N,N'-bis-(4-trimethylsilanylethynyl-phenyl)-terephthalamide (869358-31-6) → N,N'-dibutyl-N,N'-bis-[4-(4-iodo-2,5-dimethyl-phenylethynyl)-phenyl]-terephthalamide (869358-35-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.93 g / TBAF / tetrahydrofuran

2: 41 percent / Et₃N; CuI / Pd(PPh₃)4 / tetrahydrofuran / 45 - 50 °C

With copper(l) iodide; tetrabutyl ammonium fluoride; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 2: Sonogashira coupling;

DOI:10.1039/b510134d

upstream raw materials:

N,N'-dibutyl-N,N'-bis-(4-ethynyl-phenyl)-terephthalamide

2,5-diiodo-p-xylene

N,N'-dibutyl-bis(4-iodophenyl)-terephthalamide

N,N'-dibutyl-N,N'-bis-(4-trimethylsilanylethynyl-phenyl)-terephthalamide