(S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester

Base Information

• Chemical Name: (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester
• CAS No.: 209270-47-3
• Molecular Formula: C₄₅H₅₅N₇O₁₁
• Molecular Weight: 869.972

Synonyms:(S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester

Chemical Property of (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester

There total 3 articles about (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3-((S)-6-Amino-2-benzyloxycarbonylamino-hexanoylamino)-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester → (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester (209270-47-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / (benzotriazol-1-yloxy)-tris(dimethylamino)phosphonium hexafluorophosphate, N-methylmorpholine / dimethylformamide / Ambient temperature

2: H₂ / 10percent Pd/C / dimethylformamide / Ambient temperature

3: DIEA / dimethylformamide / 1 h / Ambient temperature

With 4-methyl-morpholine; hydrogen; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In N,N-dimethyl-formamide;

DOI:10.1016/S0223-5234(98)80006-8

Reference yield:

(S)-3-[(S)-6-(2-Benzyloxycarbonyl-acetylamino)-2-benzyloxycarbonylamino-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester (209270-45-1) → (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester (209270-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / dimethylformamide / Ambient temperature

2: DIEA / dimethylformamide / 1 h / Ambient temperature

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In N,N-dimethyl-formamide;

DOI:10.1016/S0223-5234(98)80006-8

Reference yield:

Cbz-L-Tryptophan-OSu (50305-28-7) + (S)-3-[(S)-2-Amino-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester → (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester (209270-47-3)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 1h; Yield given; Ambient temperature;

DOI:10.1016/S0223-5234(98)80006-8

upstream raw materials:

Cbz-L-Tryptophan-OSu

(S)-3-[(S)-6-(2-Benzyloxycarbonyl-acetylamino)-2-benzyloxycarbonylamino-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 209270-47-3 (S)-3-[(S)-2-[(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-6-(2-carboxy-acetylamino)-hexanoylamino]-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send