Technology Process of C19H23BrO5
There total 10 articles about C19H23BrO5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
methanol; dichloromethane;
at 0 - 20 ℃;
for 5h;
Inert atmosphere;
DOI:10.1016/j.tet.2011.04.094
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium tert-butylate / tetrahydrofuran / 0.5 h / -20 - -15 °C / Inert atmosphere; Cooling with acetone-dry ice
1.2: 0.25 h / -15 - 20 °C / Inert atmosphere
2.1: AD-mix-β; water / tert-butyl alcohol / 2 h / 20 °C / Inert atmosphere
3.1: triethylamine / dichloromethane / 1.75 h / 20 °C / Inert atmosphere
4.1: sodium hydride / tetrahydrofuran / 0.58 h / 0 - 20 °C / Inert atmosphere; Cooling with ice
4.2: 1 h / 20 °C / Inert atmosphere
5.1: trifluoroacetic acid / methanol; dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere
With
AD-mix-β; potassium tert-butylate; water; sodium hydride; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane; tert-butyl alcohol;
2.1: Sharpless dihydroxylation;
DOI:10.1016/j.tet.2011.04.094
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 1.75 h / 20 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran / 0.58 h / 0 - 20 °C / Inert atmosphere; Cooling with ice
2.2: 1 h / 20 °C / Inert atmosphere
3.1: trifluoroacetic acid / methanol; dichloromethane / 5 h / 0 - 20 °C / Inert atmosphere
With
sodium hydride; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1016/j.tet.2011.04.094
