3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

Base Information

Chemical Name:3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride
CAS No.:80840-63-7
Molecular Formula:C₁₉H₂₄N₄O₃S*ClH
Molecular Weight:424.952
Hs Code.:

Synonyms:3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

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Chemical Property of 3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

Chemical Property:

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Technology Process of 3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

There total 7 articles about 3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 80853-63-0
4-[2-Ethylcarbamoyl-2-(toluene-4-sulfonylamino)-ethyl]-benzimidic acid ethyl ester; hydrochloride

: 80840-63-7
3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

Guidance literature:: With ammonia; at 60 ℃; for 3h;

Reference yield:

: 52117-01-8
N-acetyl-4-cyano-α-(ethoxycarbonyl)phenylalanine ethyl ester

: 80840-63-7
3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

2: SOCl₂ / 1 h / Heating

3: 58 percent / benzene / 1.5 h / Ambient temperature

4: 45 percent / HCl(gas) / dioxane / 0 - 5 °C

5: 73 percent / NH₃ in CH₃OH / 3 h / 60 °C

With hydrogenchloride; thionyl chloride; ammonia; In 1,4-dioxane; benzene;

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 80840-63-7
3-(4-Carbamimidoyl-phenyl)-N-ethyl-2-(toluene-4-sulfonylamino)-propionamide; hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

2: SOCl₂ / 1 h / Heating

3: 58 percent / benzene / 1.5 h / Ambient temperature

4: 45 percent / HCl(gas) / dioxane / 0 - 5 °C

5: 73 percent / NH₃ in CH₃OH / 3 h / 60 °C

With hydrogenchloride; thionyl chloride; ammonia; In 1,4-dioxane; benzene;