1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene

Base Information

• Chemical Name: 1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene
• CAS No.: 949021-84-5
• Molecular Formula: C₃₇H₃₆O₆
• Molecular Weight: 576.689
• Mol file: 949021-84-5.mol

Synonyms:1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene

Chemical Property of 1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene

There total 1 articles about 1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

tributylstannylethynylbenzene (3757-88-8) + 6-O-acetyl-2,3,4-tri-O-benzyl-α-D-galactopyranosyl acetate (78185-13-4) → 1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene (949021-84-5)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 1.5h;

DOI:10.1002/ejoc.200700102

Reference yield: 45.0%

1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene (949021-84-5) + 1,2,4,5-tetrazine-3,6-dicarboxylic acid dimethyl ester (2166-14-5) → dimethyl 4-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-5-phenylpyridazine-3,6-dicarboxylate (949021-89-0)

Guidance literature:

In toluene; for 72h; Heating;

DOI:10.1002/ejoc.200700102

Reference yield:

1-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-2-phenylacetylene (949021-84-5) → dimethyl 3-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-4-phenyl-1H-pyrrole-2,5-dicarboxylate

Guidance literature:

Multi-step reaction with 2 steps

1: 45 percent / toluene / 72 h / Heating

2: 57 percent / zinc / acetic acid / 0.5 h / Heating

With zinc; In acetic acid; toluene;

DOI:10.1002/ejoc.200700102

upstream raw materials:

tributylstannylethynylbenzene

6-O-acetyl-2,3,4-tri-O-benzyl-α-D-galactopyranosyl acetate

Downstream raw materials:

dimethyl 4-(6'-O-acetyl-2',3',4'-tri-O-benzyl-α-D-galactopyranosyl)-5-phenylpyridazine-3,6-dicarboxylate