Fosalvudine tidoxil

Base Information

• Chemical Name: Fosalvudine tidoxil
• CAS No.: 763903-67-9
• Molecular Formula: C35H64 F N2 O8 P S
• Molecular Weight: 722.93
• UNII: TR856337M2
• DSSTox Substance ID: DTXSID10227221
• NCI Thesaurus Code: C170005
• Wikidata: Q1439344
• Mol file: 763903-67-9.mol

Synonyms:Fosalvudine tidoxil;763903-67-9;Fosalvudine;Fosalvudine tidoxil [INN];TR856337M2;(2-decoxy-3-dodecylsulfanylpropyl) [(2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl hydrogen phosphate;UNII-TR856337M2;HDP 99.0003;SCHEMBL7139635;DTXSID10227221;AKOS040748373;HY-14922;CS-0003635;Q1439344;(2RS)-2-(DECYLOXY)-3-((DODECYL)SULFANYL)PROPYL ((2R,3S,5R)-3-FLUORO-5-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-2-YL)METHYL HYDROGEN PHOSPHATE;2-(Decyloxy)-3-(dodecylthio)propyl (((2R,3S,5R)-3-fluoro-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) hydrogen phosphate;5'-THYMIDYLIC ACID, 3'-DEOXY-3'-FLUORO-, MONO(2-(DECYLOXY)-3-(DODECYLTHIO)PROPYL) ESTER

Chemical Property of Fosalvudine tidoxil

Chemical Property:

• PSA: 164.19000
• LogP: 8.78420
• XLogP3: 9.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 30
• Exact Mass: 722.41050334
• Heavy Atom Count: 48
• Complexity: 977

Purity/Quality:

FOSALVUDINE TIDOXIL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCSCC(COP(=O)(O)OCC1C(CC(O1)N2C=C(C(=O)NC2=O)C)F)OCCCCCCCCCC
• Isomeric SMILES: CCCCCCCCCCCCSCC(COP(=O)(O)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)F)OCCCCCCCCCC
• Recent EU Clinical Trials: A randomized, double-blind, placebo-controlled, phase II, dose finding, multicenter study to explore the safety, tolerability, efficacy, and pharmacokinetics of fosalvudine tidoxil capsules in antiretroviral na?ve patients infected with HIV-1