1,2-bis(4-bromophenyl)-1-cyanovinylene

Base Information

• Chemical Name: 1,2-bis(4-bromophenyl)-1-cyanovinylene
• CAS No.: 33731-82-7
• Molecular Formula: C₁₅H₉Br₂N
• Molecular Weight: 363.051
• Mol file: 33731-82-7.mol

Synonyms:1,2-bis(4-bromophenyl)-1-cyanovinylene

Chemical Property of 1,2-bis(4-bromophenyl)-1-cyanovinylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-bis(4-bromophenyl)-1-cyanovinylene

There total 1 articles about 1,2-bis(4-bromophenyl)-1-cyanovinylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Bromophenylacetonitrile (16532-79-9) + 4-bromo-benzaldehyde (1122-91-4) → 1,2-bis(4-bromophenyl)-1-cyanovinylene (33731-82-7)

Guidance literature:

With potassium hydroxide; In ethanol; at 20 ℃; for 1.5h;

DOI:10.1016/j.bmc.2019.04.003

Reference yield: 34.0%

1,2-bis(4-bromophenyl)-1-cyanovinylene (33731-82-7) → 2.3-Bis-<4-brom-phenyl>-propionitril (33731-83-8)

Guidance literature:

With sodium tetrahydroborate; ethanol; at 70 ℃; for 18h; Inert atmosphere;

DOI:10.1016/j.bmc.2019.04.003

Reference yield:

1,2-bis(4-bromophenyl)-1-cyanovinylene (33731-82-7) → 5-Cyan-2-<4-cyan-phenyl>-2.3-dihydro-inden (33732-09-1)

Guidance literature:

Multi-step reaction with 6 steps

1: NaBH₄ / tetrahydrofuran / Heating

2: aq. H₂SO₄ / Heating

3: (i) PCl₅, benzene, (ii) AlCl₃, PhCl

4: (i) NaBH₄, aq. iPrOH, (ii) TsOH, benzene

5: quinoline / 260 - 270 °C

6: H₂ / Pd(OH)2-BaSO₄ / acetone

With sodium tetrahydroborate; sulfuric acid; hydrogen; palladium dihydroxide; barium sulfate; In tetrahydrofuran; quinoline; acetone;

upstream raw materials:

4-Bromophenylacetonitrile

4-bromo-benzaldehyde

Downstream raw materials:

2.3-Bis-<4-brom-phenyl>-propionitril

5-Brom-2-<4-brom-phenyl>-inden

6-Cyan-2-<4-cyan-phenyl>-inden

5-Bromo-2-(4-bromo-phenyl)-3-methyl-1H-indene