4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine

Base Information

Chemical Name:4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine
CAS No.:97713-62-7
Molecular Formula:C10H9 Cl N2 O S
Molecular Weight:240.713
Hs Code.:2934100090
DSSTox Substance ID:DTXSID10357113
Wikidata:Q82136858
Mol file:97713-62-7.mol

Synonyms:97713-62-7;4-(3-chloro-4-methoxyphenyl)-1,3-thiazol-2-amine;4-(3-chloro-4-methoxyphenyl)thiazol-2-amine;Oprea1_295157;Oprea1_433223;SCHEMBL1915502;DTXSID10357113;AKOS000112123;BB 0238591;CS-0233295;EN300-13237;2-amino-4-(3-chloro-4-methoxyphenyl)thiazole;4-(3-Chloro-4-methoxy-phenyl)-thiazol-2-ylam ine;Z89239701;F2158-1761;2-PYRIDINECARBOXYLICACID,3-CHLORO-5-(TRIFLUOROMETHYL)-,ETHYLESTER

Suppliers and Price of 4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(3-Chloro-4-methoxyphenyl)thiazol-2-amine 97%
1g
$ 495.00

American Custom Chemicals Corporation
4-(3-CHLORO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
4-(3-CHLORO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
4-(3-CHLORO-4-METHOXYPHENYL)-1,3-THIAZOL-2-AMINE 95.00%
1G
$ 721.57

AK Scientific
4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine
250mg
$ 203.00

Total 3 raw suppliers

Chemical Property of 4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine

Chemical Property:

Vapor Pressure:2.3E-07mmHg at 25°C
Melting Point:179-181 °C(Solv: ethanol (64-17-5))
Boiling Point:423.1°C at 760 mmHg
PKA:4.10±0.10(Predicted)
Flash Point:209.7°C
PSA：77.11000
Density:1.37g/cm³
LogP:2.98440
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:240.0124118
Heavy Atom Count:15
Complexity:220

Purity/Quality:: 4-(3-Chloro-4-methoxyphenyl)thiazol-2-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2=CSC(=N2)N)Cl

Technology Process of 4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine

There total 3 articles about 4-(3-Chloro-4-methoxyphenyl)-1,3-thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 30095-50-2
2-bromo-1-(3-chloro-4-methoxyphenyl)ethan-1-one

: 17356-08-0
thiourea

: 97713-62-7
2-Amino-4-(3-chloro-4-methoxyphenyl)thiazole

Guidance literature:: In ethanol; for 0.5h; Heating;
DOI:10.1007/BF00770446

Reference yield:

: 766-51-8
2-Chloroanisole

: 97713-62-7
2-Amino-4-(3-chloro-4-methoxyphenyl)thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: 71 percent / SnCl₄ / 20 h / 20 °C

2: 72 percent / Br₂ / CHCl₃ / 0.33 h / 20 °C

3: 90 percent / ethanol / 0.5 h / Heating

With bromine; tin(IV) chloride; In ethanol; chloroform;
DOI:10.1007/BF00770446

Reference yield:

: 37612-52-5
4-acetyl-2-chloroanisole

: 97713-62-7
2-Amino-4-(3-chloro-4-methoxyphenyl)thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 72 percent / Br₂ / CHCl₃ / 0.33 h / 20 °C

2: 90 percent / ethanol / 0.5 h / Heating

With bromine; In ethanol; chloroform;
DOI:10.1007/BF00770446