E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene

Base Information

• Chemical Name: E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene
• CAS No.: 53235-78-2
• Molecular Formula: C₁₅H₂₀ClO₅P
• Molecular Weight: 346.748
• Mol file: 53235-78-2.mol

Synonyms:E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene

Chemical Property of E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene

There total 2 articles about E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

triethyl bromophosphonoacetate (23755-73-9) + 2-chloro-benzaldehyde (89-98-5) → E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene (53235-78-2)

Guidance literature:

With tri-n-butylarsine; at 70 ℃; for 14h;

DOI:10.1080/00397919308011152

Reference yield:

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) + 2-chloro-benzaldehyde (89-98-5) → E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene (53235-78-2)

Guidance literature:

With 4-methyl-morpholine; titanium tetrachloride; In tetrahydrofuran;

DOI:10.1016/S0040-4020(01)91461-9

Reference yield:

E-1-carbethoxy-1-diethoxyphosphoryl-2-(2-chlorophenyl) ethene (53235-78-2) + malononitrile (109-77-3) → C18H22ClN2O5P + C18H22ClN2O5P + C18H22ClN2O5P + C18H22ClN2O5P

Guidance literature:

With C₂₇H₂₆F₄IN₃O₂; In toluene; at 0 ℃; for 44h; Overall yield = 92 percent; stereoselective reaction;

DOI:10.1039/d1sc01029h

upstream raw materials:

diethoxyphosphoryl-acetic acid ethyl ester

2-chloro-benzaldehyde

triethyl bromophosphonoacetate