Benzoic acid, 4-hydrazino-2-methoxy-, methyl ester (9CI)

Base Information

• Chemical Name: Benzoic acid, 4-hydrazino-2-methoxy-, methyl ester (9CI)
• CAS No.: 763068-20-8
• Molecular Formula: C9H12 N2 O3
• Molecular Weight: 196.206
• Mol file: 763068-20-8.mol

Synonyms:Benzoicacid, 4-hydrazino-2-methoxy-, methyl ester (9CI)

Chemical Property of Benzoic acid, 4-hydrazino-2-methoxy-, methyl ester (9CI)

Chemical Property:

• Boiling Point: 352.6±32.0 °C(Predicted)
• PKA: 4.60±0.24(Predicted)
• Density: 1.242±0.06 g/cm3(Predicted)

Purity/Quality:

Methyl4-Hydrazino-2-methoxy-benzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4-hydrazino-2-methoxy-, methyl ester (9CI)

There total 3 articles about Benzoic acid, 4-hydrazino-2-methoxy-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Methyl 4-amino-2-methoxybenzoate (27492-84-8) → methyl 4-hydrazinyl-2-methoxybenzoate (763068-20-8)

Guidance literature:

Methyl 4-amino-2-methoxybenzoate; With hydrogenchloride; sodium nitrite; In water; at 0 - 2 ℃; for 1h;

With sodium metabisulfite; sodium hydroxide; In water; for 4h; pH=6.3 - 6.5; Heating / reflux;

With hydrogenchloride; In water; at 20 ℃; for 16h;

Reference yield:

methyl 4-amino-2-methoxybenzoate hemi-sulfate → methyl 4-hydrazinyl-2-methoxybenzoate (763068-20-8)

Guidance literature:

methyl 4-amino-2-methoxybenzoate hemi-sulfate; With hydrogenchloride; sodium nitrite; In water; at 15 ℃; for 1.5h;

With tin(ll) chloride; In water; at 0 - 10 ℃; for 1.5h;

Reference yield:

→ methyl 4-hydrazinyl-2-methoxybenzoate (763068-20-8)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 0 - 20 ℃;

With water; tin(ll) chloride; at 0 - 20 ℃;

upstream raw materials:

Methyl 4-amino-2-methoxybenzoate

Downstream raw materials:

C₁₂H₁₂N₂O₃

ethyl 2-methoxy-4-pyrazol-1-ylbenzoate

Refernces

• 1、 -. "THIAZOLYL-DIHYDRO-INDAZOLE". Page/Page column 19. . Retrieved 2008/06/13.