3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid

Base Information

• Chemical Name: 3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid
• CAS No.: 1228589-83-0
• Molecular Formula: C₁₈H₁₅N₃O₅S
• Molecular Weight: 385.4

Synonyms:3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid

Chemical Property of 3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid

Chemical Property:

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Technology Process of 3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid

There total 1 articles about 3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-benzyl-2,3-dihydro-6-nitro-2-thioxoquinazolin-4(1H)-one + acryloyl chloride (814-68-6,25189-84-8) → 3-(3-benzyl-6-nitro-4-oxo-3,4-dihydro-quinazolin-2-ylthio)-propanoic acid (1228589-83-0)

Guidance literature:

3-benzyl-2,3-dihydro-6-nitro-2-thioxoquinazolin-4(1H)-one; acryloyl chloride; In toluene; at 20 ℃; Cooling with ice;

With ammonia; water;

DOI:10.1016/j.bmc.2010.03.019

upstream raw materials:

acryloyl chloride

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