C₅₃H₇₇NO₁₄

Base Information

• Chemical Name: C₅₃H₇₇NO₁₄
• CAS No.: 484670-87-3
• Molecular Formula: C₅₃H₇₇NO₁₄
• Molecular Weight: 952.193
• Mol file: 484670-87-3.mol

Synonyms:C₅₃H₇₇NO₁₄

Chemical Property of C₅₃H₇₇NO₁₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₃H₇₇NO₁₄

There total 7 articles about C₅₃H₇₇NO₁₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C54H81NO17S → C53H77NO14 (484670-87-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetone; at 20 - 60 ℃; for 45h;

DOI:10.1016/j.bmc.2006.04.032

Reference yield:

C54H81NO17S (484670-86-2) → C53H77NO14 (484670-87-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetone; at 20 - 61 ℃; for 20h;

Reference yield:

C55H81NO14 → C53H77NO14 (484670-87-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 99 percent / 3-chloroperbenzoic acid / CH₂Cl₂ / 21.5 h / 0 - 20 °C

2.1: 83 percent / NaHSO₃ / tetrahydrofuran; H₂O / 0.5 h

3.1: CuBr*Me₂S / diethyl ether / -78 - -20 °C

3.2: diethyl ether / 12 h / 0 - 5 °C

3.3: 3.52 g / pyridinium para-toluenesulfonate / acetonitrile; H₂O / 48 h / 70 °C

4.1: 67 percent / Dess-Martin periodinane / CH₂Cl₂ / 30 h / -10 - -5 °C

5.1: 69 percent / pyridine / 18 h / 0 - 20 °C

6.1: 98 percent / DBU / acetone / 45 h / 20 - 60 °C

With pyridine; copper(I) bromide dimethylsulfide complex; Dess-Martin periodane; sodium hydrogensulfite; 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; diethyl ether; dichloromethane; water; acetone;

DOI:10.1016/j.bmc.2006.04.032

upstream raw materials:

C₅₃H₈₁NO₁₅

C₅₃H₇₉NO₁₅

C₅₄H₈₁NO₁₇S

Downstream raw materials:

Benzoic acid (2S,3R,4S,6R)-2-((E)-(3R,4S,5S,6R,7R,9R,13S,14R)-13,14-diethyl-4,13-dihydroxy-7-methoxy-3,5,7,9,11-pentamethyl-2,10-dioxo-oxacyclotetradec-11-en-6-yloxy)-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester

Benzoic acid (2S,3R,4S,6R)-2-((E)-(3R,5R,6R,7R,9R,13S,14R)-13,14-diethyl-13-hydroxy-7-methoxy-3,5,7,9,11-pentamethyl-2,4,10-trioxo-oxacyclotetradec-11-en-6-yloxy)-4-dimethylamino-6-methyl-tetrahydro-pyran-3-yl ester

Imidazole-1-carboxylic acid (E)-(2R,3S,7R,9R,10R,11R,13R)-10-((2S,3R,4S,6R)-3-benzoyloxy-4-dimethylamino-6-methyl-tetrahydro-pyran-2-yloxy)-2,3-diethyl-9-methoxy-5,7,9,11,13-pentamethyl-6,12,14-trioxo-oxacyclotetradec-4-en-3-yl ester