4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester

Base Information

• Chemical Name: 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester
• CAS No.: 91817-92-4
• Molecular Formula: C₁₀H₁₃ClO₃
• Molecular Weight: 216.664
• Mol file: 91817-92-4.mol

Synonyms:4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester

Chemical Property of 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester

There total 3 articles about 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

6-methyl-2,4-dioxo-cyclohexanecarboxylic acid ethyl ester (34673-07-9) → 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester (91817-92-4)

Guidance literature:

With phosphorus trichloride; In chloroform;

DOI:10.1016/S0040-4020(02)00663-4

Reference yield:

ethyl acetoacetate (141-97-9) → 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester (91817-92-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / sodium ethoxide / ethanol

2: 82 percent / phosphorus trichloride / CHCl₃

With sodium ethanolate; phosphorus trichloride; In ethanol; chloroform;

DOI:10.1016/S0040-4020(02)00663-4

Reference yield:

→ 4-chloro-6-methyl-2-oxo-cyclohex-3-enecarboxylic acid ethyl ester (91817-92-4)

Guidance literature:

Erwaermen von 2-Methyl-4,6-dioxo-cyclohexan-carbonsaeureaethylester, Chloroform, Phosphor(III)-chlorid;

upstream raw materials:

6-methyl-2,4-dioxo-cyclohexanecarboxylic acid ethyl ester

ethyl acetoacetate