2-(2-Phenylcyclohexyl)-ethanol

Base Information

• Chemical Name: 2-(2-Phenylcyclohexyl)-ethanol
• CAS No.: 343318-11-6
• Molecular Formula: C₁₄H₂₀O
• Molecular Weight: 204.312
• Mol file: 343318-11-6.mol

Synonyms:2-(2-Phenylcyclohexyl)-ethanol

Chemical Property of 2-(2-Phenylcyclohexyl)-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-Phenylcyclohexyl)-ethanol

There total 1 articles about 2-(2-Phenylcyclohexyl)-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-((1S*,2S*)-2-phenylcyclohexyl)acetate → 2-(2-Phenylcyclohexyl)-ethanol (343318-11-6)

Guidance literature:

With hydrogen; copper chromite; at 210 - 230 ℃; under 190000 Torr;

DOI:10.1021/jo01327a027

Reference yield:

2-(2-Phenylcyclohexyl)-ethanol (343318-11-6) → 4-{4-[2-(3-Carboxy-propyl)-cyclohexyl]-phenyl}-4-oxo-butyric acid (69597-09-7)

Guidance literature:

Multi-step reaction with 6 steps

1: aq. HBr, H₂SO₄ / Heating

2: NaOEt / ethanol / Heating

3: (i) KOH, aq. EtOH, (heating), (ii) (heating)

4: H₂SO₄

5: AlCl₃

6: KOH

With potassium hydroxide; aluminium trichloride; sulfuric acid; hydrogen bromide; sodium ethanolate; In ethanol;

DOI:10.1021/jo01327a027

Reference yield:

2-(2-Phenylcyclohexyl)-ethanol (343318-11-6) → 5-{2-[4-(3-Carboxy-propionyl)-phenyl]-cyclohexyl}-pentanoic acid (69597-10-0)

Guidance literature:

Multi-step reaction with 9 steps

1: aq. HBr, H₂SO₄ / Heating

2: NaOEt / ethanol / Heating

3: (i) KOH, aq. EtOH, (heating), (ii) (heating)

4: H₂SO₄

5: LiAlH₄ / diethyl ether / Heating

6: aq. HBr, H₂SO₄ / Heating

7: (i) aq. EtOH, (ii) /BRN= 1098229/, HCl

8: AlCl₃

9: KOH

With potassium hydroxide; lithium aluminium tetrahydride; aluminium trichloride; sulfuric acid; hydrogen bromide; sodium ethanolate; In diethyl ether; ethanol;

DOI:10.1021/jo01327a027

Downstream raw materials:

2'-(2-Brommethyl)-cyclohexylbenzol

4-{4-[2-(2-Carboxy-ethyl)-cyclohexyl]-phenyl}-4-oxo-butyric acid

4-{4-[2-(3-Carboxy-propyl)-cyclohexyl]-phenyl}-4-oxo-butyric acid

5-{2-[4-(3-Carboxy-propionyl)-phenyl]-cyclohexyl}-pentanoic acid