C₄₆H₆₆O₈Si₂

Base Information

• Chemical Name: C₄₆H₆₆O₈Si₂
• CAS No.: 272440-14-9
• Molecular Formula: C₄₆H₆₆O₈Si₂
• Molecular Weight: 803.196
• Mol file: 272440-14-9.mol

Synonyms:C₄₆H₆₆O₈Si₂

Chemical Property of C₄₆H₆₆O₈Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₆H₆₆O₈Si₂

There total 2 articles about C₄₆H₆₆O₈Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C39H50O7Si → C46H66O8Si2 (272440-14-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 74 percent / toluene / 3 h / 20 °C

2: 88 percent / KH; hexamethyldisilazane / tetrahydrofuran / 0.2 h / 0 °C

3: 78 percent / DIBAL / CH₂Cl₂; hexane / 0.2 h / -78 °C

With potassium hydride; diisobutylaluminium hydride; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; hexane; dichloromethane; toluene; 1: Condensation / 2: silylation / 3: Reduction;

DOI:10.1021/ja9939439

Reference yield:

C40H51NO7Si (272440-02-5) → C46H66O8Si2 (272440-14-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / KH; hexamethyldisilazane / tetrahydrofuran / 0.2 h / 0 °C

2: 78 percent / DIBAL / CH₂Cl₂; hexane / 0.2 h / -78 °C

With potassium hydride; diisobutylaluminium hydride; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; hexane; dichloromethane; 1: silylation / 2: Reduction;

DOI:10.1021/ja9939439

Reference yield: 95.0%

C46H66O8Si2 (272440-14-9) → C46H68O8Si2 (272440-05-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -78 ℃; for 0.3h;

DOI:10.1021/ja9939439

upstream raw materials:

C₄₀H₅₁NO₇Si

Downstream raw materials:

C₄₆H₆₈O₈Si₂

7-(2,2,2-trichloroethyloxycarbonyl)baccatin III

taxol

C₂₆H₃₄O₆

Refernces