C₅₂H₅₃NO₁₃

Base Information

Chemical Name:C₅₂H₅₃NO₁₃
CAS No.:273926-84-4
Molecular Formula:C₅₂H₅₃NO₁₃
Molecular Weight:899.992
Hs Code.:

C<sub>52</sub>H<sub>53</sub>NO<sub>13</sub>

Synonyms:C₅₂H₅₃NO₁₃

Suppliers and Price of C₅₂H₅₃NO₁₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₅₂H₅₃NO₁₃

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₅₂H₅₃NO₁₃

There total 14 articles about C₅₂H₅₃NO₁₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: (2R,4S,5R)-3-benzoyl-2-(p-methoxyphenyl)oxy-4-phenyl-1,3-oxazolidine-5-carboxylic acid

: 273926-83-3
C₃₆H₄₀O₁₀

: 273926-84-4
C₅₂H₅₃NO₁₃

Guidance literature:: (2R,4S,5R)-3-benzoyl-2-(p-methoxyphenyl)oxy-4-phenyl-1,3-oxazolidine-5-carboxylic acid; C₃₆H₄₀O₁₀; With dmap; dicyclohexyl-carbodiimide; In toluene; at 75 ℃; for 1.5h;

With trifluoroacetic acid; In water; at 0 - 20 ℃; for 0.666667h;
DOI:10.1016/S0040-4020(00)00073-9

Reference yield:

: 13452-36-3
2,9,10-triacetyl-5-O-cinnamoyltaxicin-I

: 273926-84-4
C₅₂H₅₃NO₁₃

Guidance literature:: Multi-step reaction with 14 steps

1.1: 70 percent / NH₂OH*HCl; NaOAc / ethanol; H₂O / 24 h / 80 °C

2.1: 81 percent / pyridine / 0.67 h / 20 °C

3.1: 81 percent / NaOMe / CH₂Cl₂; methanol / 24 h / 0 °C

4.1: 88 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

5.1: 100 percent / TBAF / tetrahydrofuran / 1 h / 20 °C

6.1: 83 percent / OsO₄; N-methylmorpholine N-oxide / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 20 h / 20 °C

7.1: 95 percent / imidazole / dimethylformamide / 3 h / 20 °C

8.1: 83 percent / pyridine / 20 h / 20 °C

9.1: TBAF / tetrahydrofuran / 1 h / 20 °C

9.2: 76 percent / TBAOAc / butan-2-one / 20 h / Heating

10.1: 93 percent / DMAP / CH₂Cl₂ / 5 h / 20 °C

11.1: 64 percent / tetrahydrofuran; cyclohexane; diethyl ether / 0.33 h / -78 °C

12.1: 70 percent / n-methylmorpholine N-oxide; tetrapropylammonium perruthenate / CH₂Cl₂ / 3 h / 20 °C

13.1: 74 percent / NaBH₄ / methanol / 3 h / 20 °C

14.1: DMAP; DCC / toluene / 1.5 h / 75 °C

14.2: 78 percent / TFA / H₂O / 0.67 h / 0 - 20 °C

With pyridine; 1H-imidazole; dmap; sodium tetrahydroborate; osmium(VIII) oxide; tetrapropylammonium perruthennate; hydroxylamine hydrochloride; tetrabutyl ammonium fluoride; sodium methylate; sodium acetate; 4-methylmorpholine N-oxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; cyclohexane; water; N,N-dimethyl-formamide; toluene; tert-butyl alcohol; 1.1: Hydrolysis / 2.1: silylation / 3.1: Deacetylation / 4.1: Carbonylation / 5.1: desilylation / 6.1: Oxidation / 7.1: silylation / 8.1: mesylation / 9.1: desylilation / 9.2: Cyclization / 10.1: Acetylation / 11.1: Phenylation / 12.1: Oxidation / 13.1: Reduction / 14.1: Esterification / 14.2: Hydrolysis;
DOI:10.1016/S0040-4020(00)00073-9

Reference yield:

: 158137-46-3
2α,9α,10β-triacetyl taxicin-I

: 273926-84-4
C₅₂H₅₃NO₁₃

Guidance literature:: Multi-step reaction with 13 steps

1.1: 81 percent / pyridine / 0.67 h / 20 °C

2.1: 81 percent / NaOMe / CH₂Cl₂; methanol / 24 h / 0 °C

3.1: 88 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

4.1: 100 percent / TBAF / tetrahydrofuran / 1 h / 20 °C

5.1: 83 percent / OsO₄; N-methylmorpholine N-oxide / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 20 h / 20 °C

6.1: 95 percent / imidazole / dimethylformamide / 3 h / 20 °C

7.1: 83 percent / pyridine / 20 h / 20 °C

8.1: TBAF / tetrahydrofuran / 1 h / 20 °C

8.2: 76 percent / TBAOAc / butan-2-one / 20 h / Heating

9.1: 93 percent / DMAP / CH₂Cl₂ / 5 h / 20 °C

10.1: 64 percent / tetrahydrofuran; cyclohexane; diethyl ether / 0.33 h / -78 °C

11.1: 70 percent / n-methylmorpholine N-oxide; tetrapropylammonium perruthenate / CH₂Cl₂ / 3 h / 20 °C

12.1: 74 percent / NaBH₄ / methanol / 3 h / 20 °C

13.1: DMAP; DCC / toluene / 1.5 h / 75 °C

13.2: 78 percent / TFA / H₂O / 0.67 h / 0 - 20 °C

With pyridine; 1H-imidazole; dmap; sodium tetrahydroborate; osmium(VIII) oxide; tetrapropylammonium perruthennate; tetrabutyl ammonium fluoride; sodium methylate; 4-methylmorpholine N-oxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; cyclohexane; water; N,N-dimethyl-formamide; toluene; tert-butyl alcohol; 1.1: silylation / 2.1: Deacetylation / 3.1: Carbonylation / 4.1: desilylation / 5.1: Oxidation / 6.1: silylation / 7.1: mesylation / 8.1: desylilation / 8.2: Cyclization / 9.1: Acetylation / 10.1: Phenylation / 11.1: Oxidation / 12.1: Reduction / 13.1: Esterification / 13.2: Hydrolysis;
DOI:10.1016/S0040-4020(00)00073-9