4-(3,4-Dimethoxyphenyl)benzyl alcohol

Base Information

• Chemical Name: 4-(3,4-Dimethoxyphenyl)benzyl alcohol
• CAS No.: 760987-73-3
• Molecular Formula: C15H16 O3
• Molecular Weight: 244.29
• Mol file: 760987-73-3.mol

Synonyms:4-(3,4-Dimethoxyphenyl)benzyl alcohol

Chemical Property of 4-(3,4-Dimethoxyphenyl)benzyl alcohol

Chemical Property:

• PSA: 38.69000
• LogP: 2.86310

Purity/Quality:

99%min ^*data from raw suppliers

(3',4'-Dimethoxy-[1,1'-biphenyl]-4-yl)methanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(3,4-Dimethoxyphenyl)benzyl alcohol

There total 2 articles about 4-(3,4-Dimethoxyphenyl)benzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-bromobenzenemethanol (873-75-6) + 3,4-Dimethoxyphenylboronic acid (122775-35-3) → 4-(3,4-dimethoxyphenyl)benzyl alcohol (760987-73-3)

Guidance literature:

With potassium phosphate; tetrabutylammomium bromide; palladium diacetate; In ethanol;

DOI:10.1039/b407324j

Reference yield:

methyl 3',4'-dimethoxybiphenyl-4-carboxylate (122294-03-5) → 4-(3,4-dimethoxyphenyl)benzyl alcohol (760987-73-3)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1021/ja907882n

Reference yield: 93.0%

5-methyl-1,3-benzodioxole (7145-99-5) + 4-(3,4-dimethoxyphenyl)benzyl alcohol (760987-73-3) → 6-(4-(3,4-dimethoxyphenyl)benzyl)-3,4-(methylenedioxy)toluene (1434832-13-9)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jo4004184

upstream raw materials:

4-bromobenzenemethanol

3,4-Dimethoxyphenylboronic acid

methyl 3',4'-dimethoxybiphenyl-4-carboxylate

Downstream raw materials:

1,5-anhydro-3-O-benzyl-6-O-(3,4-dimethoxyphenyl)benzyl-2-deoxy-4-O-(4-methoxybenzyl)-D-arabinohex-1-enitol

3’,4’-dimethoxy-[1,1’-biphenyl]-4-carbaldehyde

3-(4-(3,4-dimethoxyphenyl)benzyl)-1,4-dimethoxybenzene

3-(4-(3,4-dimethoxy-(6-(4-(3,4-dimethoxyphenyl)benzyl))phenyl)benzyl)-1,4-dimethoxybenzene

Refernces

• 1、 Liu, Xinyu,Seeberger, Peter H.. "A Suzuki-Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide". . p. 1708 - 1709. Retrieved 2007/10/03.