1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Base Information

Chemical Name:1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane
CAS No.:86933-24-6
Molecular Formula:C₂₆H₃₇NO₂
Molecular Weight:395.585
Hs Code.:

Synonyms:1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Suppliers and Price of 1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

There total 3 articles about 1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 86933-21-3
1-(3-benzyloxybenzyl)cycloheptanol

: 109-54-6
3-(Dimethylamino)propyl chloride

: 86933-24-6
1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Guidance literature:: With sodium hydride; In toluene; for 6h; Heating;
DOI:10.1248/cpb.31.1267

Reference yield:

: 24033-03-2
1-benzyloxy-3-chloromethylbenzene

: 86933-24-6
1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Mg, ethyl iodide, iodine / 1.) THF, 45 min, 0-10 deg C; 2.) THF, 20 min 10-15 deg C, then 30 min reflux

2: 54 percent / sodium hydride / toluene / 6 h / Heating

With iodine; sodium hydride; magnesium; ethyl iodide; In toluene;
DOI:10.1248/cpb.31.1267

Reference yield:

: 1700-30-7
(3-(benzyloxy)phenyl)methanol

: 86933-24-6
1-(3-benzyloxybenzyl)-1-<3-(N,N-dimethylamino)propoxy>cycloheptane

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / thionyl chloride / benzene / 2.5 h / Heating

2: 1.) Mg, ethyl iodide, iodine / 1.) THF, 45 min, 0-10 deg C; 2.) THF, 20 min 10-15 deg C, then 30 min reflux

3: 54 percent / sodium hydride / toluene / 6 h / Heating

With thionyl chloride; iodine; sodium hydride; magnesium; ethyl iodide; In toluene; benzene;
DOI:10.1248/cpb.31.1267