2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide

Base Information

Chemical Name:2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide
CAS No.:78533-11-6
Molecular Formula:C₁₈H₁₉NO₄
Molecular Weight:313.353
Hs Code.:
DSSTox Substance ID:DTXSID401212385

Synonyms:2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide;78533-11-6;DTXSID401212385;3,4-Dimethoxy-N-(2-oxo-2-phenylethyl)benzeneacetamide

Suppliers and Price of 2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:313.13140809
Heavy Atom Count:23
Complexity:393

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)CC(=O)NCC(=O)C2=CC=CC=C2)OC

Technology Process of 2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide

There total 2 articles about 2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 5468-37-1
2-aminoacetophenone hydrochloride

: 10313-60-7
3,4-dimethoxyphenylacetyl chloride

: 78533-11-6
2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide

Guidance literature:: With sodium acetate; In tetrahydrofuran; diethyl ether; Ambient temperature;
DOI:10.1002/hlca.19810640202

Reference yield:

: 93-40-3
(3,4-Dimethoxyphenyl)acetic acid

: 78533-11-6
2-(3,4-dimethoxyphenyl)-N-(2-oxo-2-phenylethyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / diethyl ether / 0.5 h / Heating

2: 69 percent / sodium acetate / diethyl ether; tetrahydrofuran / Ambient temperature

With thionyl chloride; sodium acetate; In tetrahydrofuran; diethyl ether;
DOI:10.1002/hlca.19810640202