Technology Process of Methyl4,6-O-benzylidene-3-O-(b-D-glucopyranoside)-a-D-glucopyranoside
There total 5 articles about Methyl4,6-O-benzylidene-3-O-(b-D-glucopyranoside)-a-D-glucopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
water;
at 20 ℃;
for 1.5h;
DOI:10.1021/jacs.8b10736
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: triethylamine / N,N-dimethyl-formamide / 0.5 h / 0 °C
1.2: 5.5 h / 0 - 20 °C
2.1: dichloromethane / 1 h / -60 - 20 °C / Molecular sieve
2.2: 1.5 h / -60 °C / Molecular sieve
3.1: tetrabutyl ammonium fluoride / dichloromethane / 17 h / 20 °C / Inert atmosphere; Molecular sieve
4.1: dichloromethane / 1 h / -40 - 20 °C / Molecular sieve
4.2: 0.25 h / -40 °C / Molecular sieve
5.1: trifluoroacetic acid / water / 1.5 h / 20 °C
With
tetrabutyl ammonium fluoride; triethylamine; trifluoroacetic acid;
In
dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jacs.8b10736
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: dichloromethane / 1 h / -60 - 20 °C / Molecular sieve
1.2: 1.5 h / -60 °C / Molecular sieve
2.1: tetrabutyl ammonium fluoride / dichloromethane / 17 h / 20 °C / Inert atmosphere; Molecular sieve
3.1: dichloromethane / 1 h / -40 - 20 °C / Molecular sieve
3.2: 0.25 h / -40 °C / Molecular sieve
4.1: trifluoroacetic acid / water / 1.5 h / 20 °C
With
tetrabutyl ammonium fluoride; trifluoroacetic acid;
In
dichloromethane; water;
DOI:10.1021/jacs.8b10736
