(+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane

Base Information

• Chemical Name: (+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane
• CAS No.: 126956-62-5
• Molecular Formula: C₂₅H₃₀OSSi
• Molecular Weight: 406.664
• Mol file: 126956-62-5.mol

Synonyms:(+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane

Chemical Property of (+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane

There total 1 articles about (+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(+/-)-2-(methylthio)phenethyl alcohol (70861-94-8) + tert-butylchlorodiphenylsilane (58479-61-1) → (+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane (126956-62-5)

Guidance literature:

With dmap; triethylamine; In N,N-dimethyl-formamide; for 12h; Ambient temperature;

DOI:10.1016/S0957-4166(00)80048-8

Reference yield: 90.0%

(+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane (126956-62-5) → tert-Butyl-(2-methanesulfinyl-2-phenyl-ethoxy)-diphenyl-silane (126956-69-2,126956-70-5)

Guidance literature:

With titanium(IV) isopropylate; (R)-(-)-3,5-dinitrobenzoyl)-α-ethyl phenyl amine; (+)-Weinsaeure-diethylester; In 1,2-dichloro-ethane; at -20 ℃; for 16h;

DOI:10.1016/S0040-4039(01)80528-1

Reference yield: 89.0%

(+/-)-1-(t-butyldiphenylsilyloxy)-2-(methylthio)-2-phenylethane (126956-62-5) → 1-(t-butyldiphenylsilyloxy)-2-(methylsulfinyl)-2-phenylethane (126956-69-2,126956-70-5)

Guidance literature:

With titanium(IV) isopropylate; diethyl (2R,3R)-tartrate; tert-butyl hydroperoxide (80percent, 20percent di-tert-butylperoxide, TBHP); In 1,2-dichloro-ethane; at -20 ℃; for 16h;

DOI:10.1016/S0957-4166(00)80048-8

upstream raw materials:

(+/-)-2-(methylthio)phenethyl alcohol

tert-butylchlorodiphenylsilane

Downstream raw materials:

1-(t-butyldiphenylsilyloxy)-2-(methylsulfinyl)-2-phenylethane

tert-Butyl-(2-methanesulfinyl-2-phenyl-ethoxy)-diphenyl-silane