Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo-

Base Information

Chemical Name:Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo-
CAS No.:77423-07-5
Molecular Formula:C₁₂H₁₀N₄O₃
Molecular Weight:258.236
Hs Code.:
Mol file:77423-07-5.mol

Synonyms:Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo-

Suppliers and Price of Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo-

Chemical Property:

PSA：102.48000
LogP:0.98360

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo-

There total 5 articles about Pyrazolo[5,1-b]quinazoline-2-carboxamide, 4,9-dihydro-5-methoxy-9-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76745-48-7
4,9-dihydro-5-methoxy-9-oxopyrazolo<5,1-b>quinazoline-2-carboxylic acid

: 77423-07-5
4,9-dihydro-5-methoxy-9-oxopyrazolo<5,1-b>quinazoline-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / Ambient temperature

2: 58percent aq. NH₄OH / Ambient temperature

With ammonium hydroxide; trichlorophosphate;
DOI:10.1021/jm00138a019

Reference yield:

: 3177-80-8
2-amino-3-methoxybenzoic acid

: 77423-07-5
4,9-dihydro-5-methoxy-9-oxopyrazolo<5,1-b>quinazoline-2-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: 94 percent / dioxane; benzene / Ambient temperature

2: 68 percent / 18percent aq. NH₂NH₂ / Ambient temperature

3: 2.) Na₂CO₃ / 1.) water, reflux, 1.5 h, 2.) water, reflux, 1 h

4: POCl₃ / Ambient temperature

5: 58percent aq. NH₄OH / Ambient temperature

With ammonium hydroxide; sodium carbonate; hydrazine hydrate; trichlorophosphate; In 1,4-dioxane; benzene;
DOI:10.1021/jm00138a019