N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide

Base Information

• Chemical Name: N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide
• CAS No.: 936002-62-9
• Molecular Formula: C₂₈H₃₀N₄O₃S
• Molecular Weight: 502.637

Synonyms:N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide

Chemical Property of N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide

Chemical Property:

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Technology Process of N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide

There total 1 articles about N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-(3-{(R)-2-[3-(5-cyanoindol-1-yl)-1,1-dimethylpropylamino]-1-hydroxyethyl}phenyl)dibenzenesulphonamide (936004-30-7) → N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide (936002-62-9)

Guidance literature:

N-(3-{(R)-2-[3-(5-cyanoindol-1-yl)-1,1-dimethylpropylamino]-1-hydroxyethyl}phenyl)dibenzenesulphonamide; With sodium hydroxide; ethanol; water; at 20 ℃; for 5h;

With trifluoroacetic acid; In ethanol; water;

Reference yield: 99.0%

N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide (936002-62-9) → 1-{3-[(R)-2-[3-(phenylsulphonylamino)-phenyl]-2-hydroxy-ethylamino]-3-methyl-butyl}-N-hydroxy-1H-indole-5-carboxamidine

Guidance literature:

With hydroxylamine; In ethanol; for 5h; Heating / reflux;

Reference yield: 63.0%

N-(3-{(R)-2-[3-(5-cyano-indol-1-yl)-1,1-dimethyl-propylamino]-1-hydroxy-ethyl}-phenyl)-benzenesulphonamide (936002-62-9) → N-[3-((R)-2-{1,1-dimethyl-3-[5-(tetrazol-5-yl)-indol-1-yl]-propylamino}-1-hydroxy-ethyl)-phenyl]-benzenesulphonamide

Guidance literature:

With tributyltin azide; In toluene; for 54h; Heating / reflux;

upstream raw materials:

N-(3-{(R)-2-[3-(5-cyanoindol-1-yl)-1,1-dimethylpropylamino]-1-hydroxyethyl}phenyl)dibenzenesulphonamide

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