Technology Process of C21H21N3
There total 6 articles about C21H21N3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 2h;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium acetate / palladium diacetate / N,N-dimethyl-formamide / 6 h / 80 °C
2: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 5 h / 100 °C / Inert atmosphere
3: sodium tetrahydroborate / ethanol / 2 h / 20 °C
4: potassium phosphate / tricyclohexylphosphine; palladium diacetate / toluene; water / 3 h / 100 °C
5: triphenylphosphine; di-isopropyl azodicarboxylate / toluene / 3.25 h / 0 - 20 °C
6: trifluoroacetic acid / dichloromethane / 2 h / 20 °C / Cooling with ice
With
sodium tetrahydroborate; potassium phosphate; di-isopropyl azodicarboxylate; potassium acetate; potassium carbonate; triphenylphosphine; trifluoroacetic acid;
tetrakis(triphenylphosphine) palladium(0); palladium diacetate; tricyclohexylphosphine;
In
1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
2: Suzuki Coupling / 4: Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 5 h / 100 °C / Inert atmosphere
2: sodium tetrahydroborate / ethanol / 2 h / 20 °C
3: potassium phosphate / tricyclohexylphosphine; palladium diacetate / toluene; water / 3 h / 100 °C
4: triphenylphosphine; di-isopropyl azodicarboxylate / toluene / 3.25 h / 0 - 20 °C
5: trifluoroacetic acid / dichloromethane / 2 h / 20 °C / Cooling with ice
With
sodium tetrahydroborate; potassium phosphate; di-isopropyl azodicarboxylate; potassium carbonate; triphenylphosphine; trifluoroacetic acid;
tetrakis(triphenylphosphine) palladium(0); palladium diacetate; tricyclohexylphosphine;
In
1,4-dioxane; ethanol; dichloromethane; water; toluene;
1: Suzuki Coupling / 3: Suzuki Coupling;