Technology Process of C22H22F9N3O3
There total 5 articles about C22H22F9N3O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetra-(n-butyl)ammonium iodide; potassium carbonate;
In
N,N-dimethyl-formamide;
at 90 ℃;
DOI:10.1016/j.tet.2012.07.069
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogen; 10% Pd/C / ethyl acetate / 6 h / 20 °C
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 24 h / 80 °C
3: sodium tetrahydroborate / methanol / 24 h / 20 °C
4: phosphorus tribromide; pyridine / diethyl ether / 0 - 20 °C
5: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 90 °C
With
pyridine; sodium tetrahydroborate; 10% Pd/C; hydrogen; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
methanol; diethyl ether; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2012.07.069
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium tetrahydroborate / methanol / 24 h / 20 °C
2: phosphorus tribromide; pyridine / diethyl ether / 0 - 20 °C
3: potassium carbonate; tetra-(n-butyl)ammonium iodide / N,N-dimethyl-formamide / 90 °C
With
pyridine; sodium tetrahydroborate; phosphorus tribromide; tetra-(n-butyl)ammonium iodide; potassium carbonate;
In
methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2012.07.069
