isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate

Base Information

• Chemical Name: isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate
• CAS No.: 652991-85-0
• Molecular Formula: C₂₅H₂₈O₄
• Molecular Weight: 396.479

Synonyms:isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate

Chemical Property of isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate

There total 3 articles about isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid isopropyl ester (325793-71-3) → isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H2]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate (652991-85-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 100 percent / Br₂ / CH₂Cl₂ / 2.5 h / 20 °C

2: tritium; Et₃N / Pd/C / tetrahydrofuran

3: Cs₂CO₃ / acetonitrile / 2 h / 60 °C

With tritium; bromine; caesium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1002/jlcr.725

Reference yield:

isopropyl (S)-2-ethoxy-3-(3,6-dibromo-4-hydroxyphenyl)propionate (652991-83-8) → isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H2]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate (652991-85-0)

Guidance literature:

Multi-step reaction with 2 steps

1: tritium; Et₃N / Pd/C / tetrahydrofuran

2: Cs₂CO₃ / acetonitrile / 2 h / 60 °C

With tritium; caesium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; acetonitrile;

DOI:10.1002/jlcr.725

Reference yield:

(E)-(5-chloropent-3-en-1-yn-1-yl)benzene (64907-51-3,40316-56-1) + isopropyl (S)-2-ethoxy-3-([3,5-3H2]-4-hydroxyphenyl)propionate (652991-84-9) → isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H2]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate (652991-85-0)

Guidance literature:

With caesium carbonate; In acetonitrile; at 60 ℃; for 2h;

DOI:10.1002/jlcr.725

upstream raw materials:

(E)-(5-chloropent-3-en-1-yn-1-yl)benzene

isopropyl (S)-2-ethoxy-3-([3,5-3H₂]-4-hydroxyphenyl)propionate

(S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid isopropyl ester

isopropyl (S)-2-ethoxy-3-(3,6-dibromo-4-hydroxyphenyl)propionate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 652991-85-0 isopropyl (E)(S)-2-ethoxy-3-[[3,5-3H₂]-4-(5-phenylpent-2-en-4-ynyloxy)phenyl]propionate

Send

Send

Metric Ton KG G Pound L ML

Send

Send