Technology Process of C13H15F3O4
There total 5 articles about C13H15F3O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium methylate;
In
methanol; dichloromethane;
at 5 - 20 ℃;
for 0.75h;
DOI:10.1021/ja312148q
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogenchloride / tetrahydrofuran; water / 0.25 h / 0 °C
1.2: 0.67 h / 0 °C
1.3: 2.6 h / 0 - 20 °C
2.1: copper(l) iodide; 1,10-Phenanthroline / dimethyl sulfoxide / 16 h / 70 °C
3.1: sodium methylate / dichloromethane; methanol / 0.75 h / 5 - 20 °C
With
hydrogenchloride; copper(l) iodide; 1,10-Phenanthroline; sodium methylate;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide;
1.2: |Sandmeyer Reaction / 1.3: |Sandmeyer Reaction;
DOI:10.1021/ja312148q
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: pyridine / 15 h / 20 °C / Inert atmosphere
2.1: triethylamine; palladium 10% on activated carbon; hydrogen / ethyl acetate / 1 h / 20 °C
3.1: hydrogenchloride / tetrahydrofuran; water / 0.25 h / 0 °C
3.2: 0.67 h / 0 °C
3.3: 2.6 h / 0 - 20 °C
4.1: copper(l) iodide; 1,10-Phenanthroline / dimethyl sulfoxide / 16 h / 70 °C
5.1: sodium methylate / dichloromethane; methanol / 0.75 h / 5 - 20 °C
With
pyridine; hydrogenchloride; copper(l) iodide; 1,10-Phenanthroline; palladium 10% on activated carbon; hydrogen; sodium methylate; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate;
3.2: |Sandmeyer Reaction / 3.3: |Sandmeyer Reaction;
DOI:10.1021/ja312148q
