[2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide

Base Information

• Chemical Name: [2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide
• CAS No.: 864466-21-7
• Molecular Formula: C₂₀H₂₁N₃O₂
• Molecular Weight: 335.406
• Mol file: 864466-21-7.mol

Synonyms:[2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide

Chemical Property of [2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide

There total 2 articles about [2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1,7-Dimethyl-3-p-tolylamino-benzo[4,5]furo[2,3-c]pyran-2-ylium; perchlorate → [2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide (864466-21-7)

Guidance literature:

With hydrazine hydrate; In isopropyl alcohol; for 0.5h; Heating;

DOI:10.1002/jhet.5570420510

Reference yield:

benzo[b]furan-3-acetic acid 2-acetyl-6-methyl-(4-methylphenyl)amide (501910-02-7) → [2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide (864466-21-7)

Guidance literature:

With hydrazine hydrate; In isopropyl alcohol; for 0.5h; Heating;

DOI:10.1007/s10593-005-0181-9

Reference yield: 98.0%

[2-(1-hydrazono-ethyl)-6-methylbenzo[b]furan-3-yl]acetic acid N-(4-methylphenyl)amide (864466-21-7) → (6-methyl-3-(p-tolylcarbamoyl-methyl)benzo[b]furan-2-yl)methyl ketone azine

Guidance literature:

In acetic acid; for 1h; Heating;

DOI:10.1002/jhet.5570420510

upstream raw materials:

benzo[b]furan-3-acetic acid 2-acetyl-6-methyl-(4-methylphenyl)amide

Downstream raw materials:

2-{2-[1-(acetylhydrazono)-ethyl]-6-methylbenzo[b]furan-3-yl}-N-p-tolylacetamide