C₂₇H₄₀O₅

Base Information

• Chemical Name: C₂₇H₄₀O₅
• CAS No.: 1451195-82-6
• Molecular Formula: C₂₇H₄₀O₅
• Molecular Weight: 444.612
• Mol file: 1451195-82-6.mol

Synonyms:C₂₇H₄₀O₅

Chemical Property of C₂₇H₄₀O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₄₀O₅

There total 26 articles about C₂₇H₄₀O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

C27H40O4 (1451195-81-5) → C27H40O5 (1451195-82-6)

Guidance literature:

With disodium hydrogenphosphate; 2-methyl-but-2-ene; sodium chlorite; In water; tert-butyl alcohol; at 0 - 20 ℃; for 1h;

DOI:10.1271/bbb.130243

Reference yield:

C9H16O (1451195-61-1) → C27H40O5 (1451195-82-6)

Guidance literature:

Multi-step reaction with 8 steps

1.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 0.33 h / 0 - 20 °C

2.1: N,N-dimethyl-formamide / 0 - 20 °C

3.1: n-butyllithium / tetrahydrofuran / 0.33 h / -78 °C

3.2: 1 h / -78 - 20 °C

4.1: Dess-Martin periodane / dichloromethane / 0.25 h / 0 - 20 °C

5.1: aluminum amalgam; disodium hydrogenphosphate / methanol / 3 h / 0 - 20 °C

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 0 - 20 °C

7.1: Dess-Martin periodane / dichloromethane / 5 h / 0 - 20 °C

8.1: disodium hydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / tert-butyl alcohol; water / 1 h / 0 - 20 °C

With disodium hydrogenphosphate; aluminum amalgam; n-butyllithium; 2-methyl-but-2-ene; carbon tetrabromide; sodium chlorite; tetrabutyl ammonium fluoride; Dess-Martin periodane; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1271/bbb.130243

Reference yield:

C9H15Br (1451195-62-2) → C27H40O5 (1451195-82-6)

Guidance literature:

Multi-step reaction with 7 steps

1.1: N,N-dimethyl-formamide / 0 - 20 °C

2.1: n-butyllithium / tetrahydrofuran / 0.33 h / -78 °C

2.2: 1 h / -78 - 20 °C

3.1: Dess-Martin periodane / dichloromethane / 0.25 h / 0 - 20 °C

4.1: aluminum amalgam; disodium hydrogenphosphate / methanol / 3 h / 0 - 20 °C

5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 0 - 20 °C

6.1: Dess-Martin periodane / dichloromethane / 5 h / 0 - 20 °C

7.1: disodium hydrogenphosphate; sodium chlorite; 2-methyl-but-2-ene / tert-butyl alcohol; water / 1 h / 0 - 20 °C

With disodium hydrogenphosphate; aluminum amalgam; n-butyllithium; 2-methyl-but-2-ene; sodium chlorite; tetrabutyl ammonium fluoride; Dess-Martin periodane; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1271/bbb.130243

upstream raw materials:

C₉H₁₆O

C₉H₁₅Br

C₁₆H₂₂O₂S

9-Decen-1-ol

Downstream raw materials:

(9R,12S,13R,15Z)-9-hydroxy-12,13-methylene-10-oxooctadec-15-enoic acid