{2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine

Base Information

• Chemical Name: {2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine
• CAS No.: 1139717-85-3
• Molecular Formula: C₁₅H₁₇ClN₂O₂
• Molecular Weight: 292.765
• Mol file: 1139717-85-3.mol

Synonyms:{2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine

Chemical Property of {2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine

Chemical Property:

Purity/Quality:

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Technology Process of {2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine

There total 1 articles about {2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.0%

6-chloropyridine-3-ol (41288-96-4) + 3-(2-(dimethylamino)ethoxy)phenylboronic acid (1139717-84-2) → {2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine (1139717-85-3)

Guidance literature:

With triethylamine; copper diacetate; In dichloromethane; for 72h; Molecular sieve; under air;

Reference yield: 10.0%

{2-[3-(6-chloropyridin-3-yloxy)phenoxy]ethyl}dimethylamine (1139717-85-3) + 4-fluoro-3-methoxyaniline (64465-53-8) → {5-[3-(2-(dimethylamino)ethoxy)phenoxy]pyridine-2-yl}-(4-fluoro-3-methoxyphenyl)amine (1139717-87-5)

Guidance literature:

With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 80 ℃; for 48h;

upstream raw materials:

6-chloropyridine-3-ol

3-(2-(dimethylamino)ethoxy)phenylboronic acid

Downstream raw materials:

{5-[3-(2-(dimethylamino)ethoxy)phenoxy]pyridine-2-yl}-(4-fluoro-3-methoxyphenyl)amine