3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Base Information

Chemical Name:3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol
CAS No.:757951-49-8
Molecular Formula:C₄₂H₇₄O₄
Molecular Weight:643.047
Hs Code.:

Synonyms:3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Suppliers and Price of 3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

There total 15 articles about 3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 222984-14-7
1-O-benzyl-2-O-(R)-3,7-dimethyloctyl-sn-glycerol

: 757951-49-8
3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Guidance literature:: Multi-step reaction with 6 steps

1.1: p-TsOH / CH₂Cl₂ / 20 °C

2.1: 1.26 g / H₂ / Pd/C / ethanol

3.1: NaH / tetrahydrofuran / 0.25 h

3.2: Bu₄NBr / tetrahydrofuran / 5 h

4.1: 1.08 g / p-TsOH / methanol / 20 °C

5.1: 2,6-lutidine / CH₂Cl₂ / 0.25 h

6.1: KH / tetrahydrofuran

6.2: 900 mg / tetrahydrofuran / 20 °C

With 2,6-dimethylpyridine; hydrogen; potassium hydride; sodium hydride; toluene-4-sulfonic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1021/ja049805n

Reference yield:

: 2-[(R)-3-Benzyloxy-2-((R)-3,7-dimethyl-octyloxy)-propoxy]-tetrahydro-pyran

: 757951-49-8
3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1.26 g / H₂ / Pd/C / ethanol

2.1: NaH / tetrahydrofuran / 0.25 h

2.2: Bu₄NBr / tetrahydrofuran / 5 h

3.1: 1.08 g / p-TsOH / methanol / 20 °C

4.1: 2,6-lutidine / CH₂Cl₂ / 0.25 h

5.1: KH / tetrahydrofuran

5.2: 900 mg / tetrahydrofuran / 20 °C

With 2,6-dimethylpyridine; hydrogen; potassium hydride; sodium hydride; toluene-4-sulfonic acid; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1021/ja049805n

Reference yield:

: 757951-48-7
Trifluoro-methanesulfonic acid (R)-3-allyloxy-2-((R)-3,7-dimethyl-octyloxy)-propyl ester

: (cis-4,7-methylidene)-18-benzyloxyoctadecan-1-ol

: 757951-49-8
3-O-[1-octadecan-(cis-4,7-methylidene)-18-benzyloxy-methylene]-2-O-[3-(R)-7-dimethyloctyl]-1-O-allyl-sn-glycerol

Guidance literature:: (cis-4,7-methylidene)-18-benzyloxyoctadecan-1-ol; With potassium hydride; In tetrahydrofuran;

Trifluoro-methanesulfonic acid (R)-3-allyloxy-2-((R)-3,7-dimethyl-octyloxy)-propyl ester; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/ja049805n