3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid

Base Information

Chemical Name:3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid
CAS No.:439612-19-8
Molecular Formula:C₂₀H₁₈Cl₂N₂O₄
Molecular Weight:421.28
Hs Code.:

Synonyms:3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid

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Technology Process of 3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid

There total 2 articles about 3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 439612-18-7
methyl 3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxo-propanoate

: 439612-19-8
3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid

Guidance literature:: With sodium hydroxide; In diethyl ether; ethanol; dichloromethane;

Reference yield:

: 439612-45-0
3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]aniline

: 439612-19-8
3-({3,5-dichloro-4-[(3-isopropyl-1H-indol-5-yl)oxy]phenyl}amino)-3-oxopropionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane; acetone

2: sodium hydroxide / diethyl ether; ethanol; dichloromethane

With sodium hydroxide; triethylamine; In diethyl ether; ethanol; dichloromethane; acetone;