Phenol, 4-(2-amino-1-methylethyl)-, (S)- (9CI)

Base Information

• Chemical Name: Phenol, 4-(2-amino-1-methylethyl)-, (S)- (9CI)
• CAS No.: 757153-78-9
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• Mol file: 757153-78-9.mol

Synonyms:Phenol,4-(2-amino-1-methylethyl)-, (S)- (9CI)

Chemical Property of Phenol, 4-(2-amino-1-methylethyl)-, (S)- (9CI)

Chemical Property:

• Boiling Point: 267℃
• Flash Point: 115℃
• Density: 1.067

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenol, 4-(2-amino-1-methylethyl)-, (S)- (9CI)

There total 6 articles about Phenol, 4-(2-amino-1-methylethyl)-, (S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C16H17NO3 → 4-(β-Amino-isopropyl)-phenol (90765-58-5,757153-78-9)

Guidance literature:

With palladium on activated carbon; hydrogen; In methanol; at 20 ℃; for 18h; Sealed tube;

DOI:10.1002/anie.201806490

Reference yield:

1-amino-2-(4-methoxyphenyl)-propane (51558-14-6,127201-17-6,127201-18-7) → 4-(β-Amino-isopropyl)-phenol (90765-58-5,757153-78-9)

Guidance literature:

With hydrogen iodide;

Reference yield:

3-(4-Methoxyphenyl)butanamid (6555-31-3) → 4-(β-Amino-isopropyl)-phenol (90765-58-5,757153-78-9)

Guidance literature:

Multi-step reaction with 2 steps

1: alkaline aqueous sodium hypobromite / anschliessendes Erwaermen mit Natriumhydroxid

2: aqueous hydrochloric acid / 160 °C

With hydrogenchloride; alkaline aqueous sodium hypobromite;

DOI:10.1021/ja01272a026

upstream raw materials:

1-amino-2-(4-methoxyphenyl)-propane

2-(4-methoxy-phenyl)-propionaldehyde-oxime

3-(4-Methoxyphenyl)butanamid

p-benzyloxybenzaldehyde

Refernces