Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

Base Information

Chemical Name:Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester
CAS No.:78778-23-1
Molecular Formula:C₁₉H₂₇BrN₂O₃
Molecular Weight:411.339
Hs Code.:

Synonyms:Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

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Chemical Property of Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

Chemical Property:

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Technology Process of Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

There total 4 articles about Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₉H₂₅BrClNO₃

: 78778-23-1
Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

Guidance literature:: With ammonia; In toluene; at 20 - 22 ℃; for 48h;

Reference yield:

: 49788-04-7,62114-09-4,62114-10-7,119343-45-2,119365-84-3
4(β)-hydroxy-trans-decahydroquinoleine

: 78778-23-1
Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: Na₂CO₃ / butan-1-ol / 72 h / Heating

2: toluene / 48 h / 20 - 22 °C

3: NH₃ / toluene / 48 h / 20 - 22 °C

With ammonia; sodium carbonate; In toluene; butan-1-ol;

Reference yield:

: (4R,4aS,8aS)-1-[3-(4-Bromo-phenoxy)-propyl]-decahydro-quinolin-4-ol

: 78778-23-1
Carbamic acid (4R,4aS,8aS)-1-[3-(4-bromo-phenoxy)-propyl]-decahydro-quinolin-4-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 48 h / 20 - 22 °C

2: NH₃ / toluene / 48 h / 20 - 22 °C

With ammonia; In toluene;