5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

Base Information

Chemical Name:5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole
CAS No.:1064702-29-9
Molecular Formula:C₁₄H₁₄Cl₂N₂O₂
Molecular Weight:313.183
Hs Code.:

Synonyms:5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

Suppliers and Price of 5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

There total 4 articles about 5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.4%

: 1064702-28-8
C₁₄H₁₆Cl₂N₂O₃

: 1064702-29-9
5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

Guidance literature:: In toluene; at 145 ℃; for 16h;

Reference yield:

: 3648-74-6
4-(4-chlorophenyl)tetrahydro-2H-pyran-4-carbonitrile

: 1064702-29-9
5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydroxylamine hydrochloride; sodium ethanolate / ethanol / 16 h / 110 °C

1.2: pH 6 - 7

2.1: potassium carbonate / acetone / 2 h / 0 - 20 °C

3.1: toluene / 16 h / 145 °C

With hydroxylamine hydrochloride; sodium ethanolate; potassium carbonate; In ethanol; acetone; toluene;

Reference yield:

: 1064702-27-7
4-(4-chloro-phenyl)-N-hydroxy-tetrahydro-pyran-4-carboxamidine

: 1064702-29-9
5-chloromethyl-3-[4-(4-chloro-phenyl)-tetrahydro-pyran-4-yl]-[1,2,4]oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 2 h / 0 - 20 °C

2: toluene / 16 h / 145 °C

With potassium carbonate; In acetone; toluene;