L-VALINE-2-D1

Base Information

• Chemical Name: L-VALINE-2-D1
• CAS No.: 77257-03-5
• Molecular Formula: C5H10 D N O2
• Molecular Weight: 118.15
• Mol file: 77257-03-5.mol

Synonyms:L-VALINE-2-D1

Chemical Property of L-VALINE-2-D1

Chemical Property:

• PSA: 63.32000
• LogP: 0.75460
• Storage Temp.: Refrigerator
• Solubility.: Aqueous Acid (Slightly, Heated, Sonicated), Methanol (Slightly, Heated), Water (

Purity/Quality:

99% ^*data from raw suppliers

L-Valine-2-d1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: L-Valine-2-d1 (CAS# 77257-03-5) is a useful isotopically labeled research compound.

Technology Process of L-VALINE-2-D1

There total 7 articles about L-VALINE-2-D1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) → α-2H-(S)-valine (77257-03-5)

Guidance literature:

In water-d2; at 30 ℃; for 24h; potassium-phophate buffer, pyridoxal-5'-phosphate, lyophilized E_. coli cells containing tryptophanase, anaerobic incubation;

DOI:10.1016/S0040-4039(00)97240-X

Reference yield:

C30H26(2)H2Cl3N3NiO3 → α-2H-(S)-valine (77257-03-5)

Guidance literature:

With hydrogenchloride; In methanol; water; at 50 ℃; for 5h;

DOI:10.1039/c7ob01720k

Reference yield:

sodium 3-methyl-2-oxobutyrate (3715-29-5) → D-<2-2H>valine (77257-02-4) + α-2H-(S)-valine (77257-03-5)

Guidance literature:

With zinc(II) perchlorate; (R)-15-aminomethyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane; In deuteromethanol; for 96h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

DOI:10.1246/bcsj.56.3652

upstream raw materials:

L-valine

Ac-DL-<2-2H>Val

sodium 3-methyl-2-oxobutyrate

C₁₄H₁₈⁽²⁾HNO₃

Downstream raw materials:

(L-α-amino-δ-adipyl)-L-cysteinyl-D-valine