1-(2-chloro-5-[⁽¹¹⁾C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

Base Information

• Chemical Name: 1-(2-chloro-5-[⁽¹¹⁾C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
• CAS No.: 1150313-56-6
• Molecular Formula: C₂₂H₂₃ClN₂O
• Molecular Weight: 365.879

Synonyms:1-(2-chloro-5-[⁽¹¹⁾C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

Chemical Property of 1-(2-chloro-5-[⁽¹¹⁾C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

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Technology Process of 1-(2-chloro-5-[⁽¹¹⁾C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide

There total 1 articles about 1-(2-chloro-5-[⁽¹¹⁾C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

[11C]methyl iodide (54245-42-0) + 1-(2-chloro-5-tri-n-butylstannylphenyl)-N-methyl-(1-methylpropyl)-3-isoquinolinecarboxamide (1150313-72-6) → 1-(2-chloro-5-[(11)C]methylphenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide (1150313-56-6)

Guidance literature:

With potassium carbonate; copper(l) chloride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tris-(o-tolyl)phosphine; In N,N-dimethyl-formamide; at 65 ℃; for 0.0833333h;

upstream raw materials:

[11C]methyl iodide

1-(2-chloro-5-tri-n-butylstannylphenyl)-N-methyl-(1-methylpropyl)-3-isoquinolinecarboxamide

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