(S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Base Information

Chemical Name:(S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide
CAS No.:1043453-98-0
Molecular Formula:C₂₄H₃₁F₂NO₂
Molecular Weight:403.512
Hs Code.:

Synonyms:(S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Suppliers and Price of (S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

There total 7 articles about (S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

: 1043453-99-1
(R)-4-Benzyl-3-[(S)-2-(4-fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoyl]-oxazolidin-2-one

: 1043453-98-0
(S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Guidance literature:: With hydroxylamine; potassium cyanide; In tetrahydrofuran; methanol; water; at 20 ℃;

Reference yield:

: C₃₀H₃₉F₂NO₃

: 1043453-98-0
(S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Guidance literature:: With potassium cyanide; hydroxylamine monohydrate; In tetrahydrofuran; methanol; at 20 ℃;
DOI:10.1016/j.bmcl.2011.02.010

Reference yield:

: C₂₁H₃₀FNO₃

: 1043453-98-0
(S)-2-(4-Fluoro-3,5-dimethyl-benzyl)-8-(4-fluoro-3-methyl-phenyl)-octanoic acid hydroxyamide

Guidance literature:: Multi-step reaction with 2 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C

2: potassium cyanide; hydroxylamine monohydrate / tetrahydrofuran; methanol / 20 °C

With potassium cyanide; hydroxylamine monohydrate; lithium hexamethyldisilazane; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2011.02.010