Technology Process of 2-methyl-1-oxo-3,4-diphenyl-1,2-dihydroisoquinolin-6-yl acetate
There total 3 articles about 2-methyl-1-oxo-3,4-diphenyl-1,2-dihydroisoquinolin-6-yl acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper(II) acetate monohydrate;
In
tert-Amyl alcohol;
at 100 ℃;
for 22h;
Inert atmosphere;
DOI:10.1002/anie.201101943
- Guidance literature:
-
Multi-step reaction with 2 steps
1: potassium carbonate / diethyl ether / 20 °C
2: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper(II) acetate monohydrate / tert-Amyl alcohol / 22 h / 100 °C / Inert atmosphere
With
[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper(II) acetate monohydrate; potassium carbonate;
In
tert-Amyl alcohol; diethyl ether;
DOI:10.1002/anie.201101943
- Guidance literature:
-
Multi-step reaction with 3 steps
1: thionyl chloride / N,N-dimethyl-formamide / 1 h / 80 °C / Inert atmosphere
2: potassium carbonate / diethyl ether / 20 °C
3: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper(II) acetate monohydrate / tert-Amyl alcohol / 22 h / 100 °C / Inert atmosphere
With
thionyl chloride; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; copper(II) acetate monohydrate; potassium carbonate;
In
tert-Amyl alcohol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1002/anie.201101943
