Technology Process of C33H46N4O12
There total 9 articles about C33H46N4O12 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydroxylamine hydrochloride; potassium hydroxide;
In
methanol;
at 20 ℃;
for 24h;
Inert atmosphere;
DOI:10.1021/bc400074w
- Guidance literature:
-
Multi-step reaction with 7 steps
1: caesium carbonate / N,N-dimethyl-formamide / 80 °C
2: lithium hydroxide / tetrahydrofuran; methanol; water / 5 h / 20 °C
3: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol; TBTU / N,N-dimethyl-formamide; water / 23.5 h / 20 °C
4: dichloromethane / 0 - 20 °C
5: triethylamine / dichloromethane / 0 - 20 °C
6: triphenylphosphine; water / tetrahydrofuran / 48 h / 20 °C
7: potassium hydroxide; hydroxylamine hydrochloride / methanol / 24 h / 20 °C / Inert atmosphere
With
TBTU; hydroxylamine hydrochloride; water; benzotriazol-1-ol; caesium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; potassium hydroxide; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
6: |Staudinger Azide Reduction;
DOI:10.1021/bc400074w
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / 0 - 20 °C
2: triphenylphosphine; water / tetrahydrofuran / 48 h / 20 °C
3: potassium hydroxide; hydroxylamine hydrochloride / methanol / 24 h / 20 °C / Inert atmosphere
With
hydroxylamine hydrochloride; water; triethylamine; triphenylphosphine; potassium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane;
2: |Staudinger Azide Reduction;
DOI:10.1021/bc400074w
