(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid

Base Information

Chemical Name:(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid
CAS No.:1432500-66-7
Molecular Formula:C₂₆H₂₆N₂O₅
Molecular Weight:446.503
Hs Code.:

Synonyms:(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid

Suppliers and Price of (1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ML334
5mg
$ 1800.00

Tocris
ML334 ≥98%(HPLC)
5
$ 135.00

ChemScene
ML334 99.82%
10mg
$ 950.00

ChemScene
ML334 99.82%
5mg
$ 555.00

ChemScene
ML334 99.82%
1mg
$ 185.00

Axon Medchem
ML334-LH601A 99%
25 mg
$ 484.00

American Custom Chemicals Corporation
ML 334 95.00%
5MG
$ 498.10

AK Scientific
(1S,2R)-2-[(1S)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylicacid
10mg
$ 394.00

AK Scientific
(1S,2R)-2-[(1S)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylicacid
5mg
$ 276.00

AK Scientific
(1S,2R)-2-[(1S)-1-[(1,3-Dioxoisoindol-2-yl)methyl]-3,4-dihydro-1H-isoquinoline-2-carbonyl]cyclohexane-1-carboxylicacid
1mg
$ 139.00

Total 5 raw suppliers

Chemical Property of (1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid

Chemical Property:

Boiling Point:693.1±55.0 °C(Predicted)
Density:1.354±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

ML334 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses ML 334 is an inhibitor of Keap1-Nrf2 interaction and affects the cytoprotective responses to oxidative and electrophilic stress. May be used in cancer treatment and attenuation.

Technology Process of (1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid

There total 32 articles about (1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 1432065-37-6
benzyl-(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinoline-2-carbonyl]cyclohexane-1-carboxylate

: 1432500-66-7
(1S,2R)-2-[(1S)-1-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-carbonyl]cyclohexane-1-carboxylic acid

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In tetrahydrofuran; ethanol; ethyl acetate; for 48h; stereoselective reaction;
DOI:10.1002/cmdc.201300525