ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate

Base Information

• Chemical Name: ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate
• CAS No.: 1231733-96-2
• Molecular Formula: C₃₀H₃₈N₂O₆S
• Molecular Weight: 554.708
• Mol file: 1231733-96-2.mol

Synonyms:ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate

Chemical Property of ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate

There total 1 articles about ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.3%

ethyl 2-((4,6-dihydroxypyrimidin-2-yl)thio)hexanoate (916482-23-0) + 4-methoxyphenethyl bromide (14425-64-0) → ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate (1231733-96-2)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 - 90 ℃; for 21h;

DOI:10.1021/jm1003073

Reference yield: 89.4%

ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate (1231733-96-2) → 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoic acid (1231733-73-5)

Guidance literature:

ethyl 2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 25 - 50 ℃; for 5h;

With hydrogenchloride; In water;

DOI:10.1021/jm1003073

upstream raw materials:

ethyl 2-((4,6-dihydroxypyrimidin-2-yl)thio)hexanoate

4-methoxyphenethyl bromide

Downstream raw materials:

2-(4,6-bis(4-methoxyphenethoxy)pyrimidin-2-ylthio)hexanoic acid