Technology Process of C48H52FN7O4S
There total 7 articles about C48H52FN7O4S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: trifluoroacetic acid
2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 43 h / 0 - 20 °C
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid;
In
N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.04.032
- Guidance literature:
-
Multi-step reaction with 3 steps
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane
2: trifluoroacetic acid
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 43 h / 0 - 20 °C
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; trifluoroacetic acid;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2012.04.032
- Guidance literature:
-
Multi-step reaction with 7 steps
1: triethylamine / tetrahydrofuran; water
2: sulfuric acid / tetrahydrofuran
3: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran
4: potassium carbonate; thiophenol / N,N-dimethyl-formamide
5: sodium tris(acetoxy)borohydride / dichloromethane
6: trifluoroacetic acid
7: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 43 h / 0 - 20 °C
With
sulfuric acid; sodium tris(acetoxy)borohydride; potassium carbonate; thiophenol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; trifluoroacetic acid; diethylazodicarboxylate;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;
3: Mitsunobu reaction;
DOI:10.1016/j.bmcl.2012.04.032