(S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate

Base Information

• Chemical Name: (S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate
• CAS No.: 1392824-55-3
• Molecular Formula: C₁₇H₂₁NO₇
• Molecular Weight: 351.356
• Mol file: 1392824-55-3.mol

Synonyms:(S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate

Chemical Property of (S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate

There total 1 articles about (S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(E)-2-methoxy-6-(2-nitrovinyl)phenol (1986-06-7,141849-32-3) + 2-ethoxycarbonyl-1-cyclopentanone (611-10-9) → (S)-ethyl 1-[(R)-1-(2-hydroxy-3-methoxyphenyl)-2-nitroethyl]-2-oxocyclopentanecarboxylate (1392824-55-3)

Guidance literature:

With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((S)-(6-methoxyquinolin-4-yl)((2S,4S,8R)-8-vinylquinuclidin-2-yl)methyl)thiourea; In dichloromethane; at 25 ℃; optical yield given as %ee;

DOI:10.1039/c2ob07122c

upstream raw materials:

(E)-2-methoxy-6-(2-nitrovinyl)phenol

2-ethoxycarbonyl-1-cyclopentanone