2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol

Base Information

• Chemical Name: 2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol
• CAS No.: 52372-28-8
• Molecular Formula: C₁₆H₁₆BrNO₂
• Molecular Weight: 334.213
• Mol file: 52372-28-8.mol

Synonyms:2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol

Chemical Property of 2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol

There total 2 articles about 2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(1S,2R)-(+)-norphedrine (37577-28-9,58550-13-3,757124-50-8) + 5-bromosalicyclaldehyde (1761-61-1) → 2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol (52372-28-8)

Guidance literature:

In methanol; for 2h; Reflux;

DOI:10.1039/c0nj00179a

Reference yield:

Acutrim (40626-29-7) + 5-bromosalicyclaldehyde (1761-61-1) → 2-[{(1S,2R)-1-hydroxy-1-phenylpropan-2-ylimino}methyl]-4-bromophenol (52372-28-8)

Guidance literature:

Acutrim; With potassium carbonate; In ethanol; at 27 ℃; for 0.5h;

5-bromosalicyclaldehyde; In ethanol; at 27 ℃; for 4h;

DOI:10.1111/j.1747-0285.2011.01263.x

upstream raw materials:

(1S,2R)-(+)-norphedrine

5-bromosalicyclaldehyde

Acutrim