BENZIL-D10

Base Information

• Chemical Name: BENZIL-D10
• CAS No.: 77092-81-0
• Molecular Formula: C14D10 O2
• Molecular Weight: 220.29
• Mol file: 77092-81-0.mol

Synonyms:Ethanedione,di(phenyl-d5)- (9CI); Benzil-d10

Chemical Property of BENZIL-D10

Chemical Property:

• PSA: 34.14000
• LogP: 2.75220

Purity/Quality:

99% by HPLC; ≥98% atom D ^*data from raw suppliers

Benzil-d10 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Benzil-d10 (CAS# 77092-81-0) is a useful isotopically labeled research compound.

Technology Process of BENZIL-D10

There total 3 articles about BENZIL-D10 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

di(d5-phenyl)acetylene (19339-46-9) → [D10]-benzil (77092-81-0)

Guidance literature:

With potassium permanganate; sodium hydrogencarbonate; magnesium sulfate; In water; acetone; at 20 ℃; for 24h;

DOI:10.1021/acs.orglett.0c01260

Reference yield:

bromobenzene-d5 (4165-57-5) → [D10]-benzil (77092-81-0)

Guidance literature:

Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene; water / 10 h / 80 °C / Schlenk technique; Inert atmosphere

2: sodium hydrogencarbonate; magnesium sulfate; potassium permanganate / water; acetone / 24 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; potassium permanganate; copper(l) iodide; sodium hydrogencarbonate; magnesium sulfate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In water; acetone; toluene;

DOI:10.1021/acs.orglett.0c01260

Reference yield:

→ [D10]-benzil (77092-81-0)

Guidance literature:

Benzoin-d10, NaOMe, I2;

DOI:10.1016/S0040-4020(01)91464-4

upstream raw materials:

di(d₅-phenyl)acetylene

bromobenzene-d5